Howard Halpern, MD PhD

Howard J. Halpern, MD, PhD, specializes in medical imaging techniques. He is an expert in very low frequency-imaging-electron paramagnetic resonance (VLF-I-EPR). This technique enables measurement of changes in oxygen content in tumor tissues--a key determinant of response to radiation therapy.



Dr. Halpern is the co-author of a textbook on free radical biology. He serves as the principal investigator for the Oversight Committee for the Laboratory Training of Radiation Oncology Residents.

University of Wisconsin
Madison, Wisconsin
PhD - High Energy Physics
1976

University of Miami
Miami, Florida
MD - Medicine
061980

Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI.
Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI. J Magn Reson. 2024 Mar 12; 361:107654.
PMID: 38492546

Directional TV algorithm for fast EPR imaging.
Directional TV algorithm for fast EPR imaging. J Magn Reson. 2024 Mar 01; 361:107652.
PMID: 38457937

Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models.
Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models. Front Med (Lausanne). 2023; 10:1339872.
PMID: 38116039

Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models.
Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models. Front Med (Lausanne). 2023; 10:1269689.
PMID: 37904839

A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module.
A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module. IEEE Trans Radiat Plasma Med Sci. 2023 Nov; 7(8):794-801.
PMID: 37981977

Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance.
Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance. Antioxid Redox Signal. 2023 May 04.
PMID: 36680741

A Simple but Universal Fully Linearized ADMM Algorithm for Optimization Based Image Reconstruction.
A Simple but Universal Fully Linearized ADMM Algorithm for Optimization Based Image Reconstruction. Res Sq. 2023 Apr 28.
PMID: 37162853

4D-image reconstruction directly from limited-angular-range data in continuous-wave electron paramagnetic resonance imaging.
4D-image reconstruction directly from limited-angular-range data in continuous-wave electron paramagnetic resonance imaging. J Magn Reson. 2023 May; 350:107432.
PMID: 37058955

An iterative reconstruction algorithm without system matrix for EPR imaging.
An iterative reconstruction algorithm without system matrix for EPR imaging. J Magn Reson. 2022 Nov; 344:107307.
PMID: 36308904

The optimal 18F-fluoromisonidazole PET threshold to define tumor hypoxia in preclinical squamous cell carcinomas using pO2 electron paramagnetic resonance imaging as reference truth.
The optimal 18F-fluoromisonidazole PET threshold to define tumor hypoxia in preclinical squamous cell carcinomas using pO2 electron paramagnetic resonance imaging as reference truth. Eur J Nucl Med Mol Imaging. 2022 Oct; 49(12):4014-4024.
PMID: 35792927

View All Publications