I have established my career through the development and evaluation of computerized techniques for the quantitative analysis of medical images and the assessment of tumor response to therapy. More specifically, my research has involved the computerized detection and evaluation of lung nodules in thoracic computed tomography (CT) scans, the assessment of image quality and pathologic change in temporally subtracted chest radiographic images, the computerized evaluation of mesothelioma tumor and response to therapy in CT scans, critical analyses of image-based tumor response assessment for mesothelioma, the development of objective CT-based metrics for the quantification of mucosal inflammation due to sinusitis, the application of radiomics to the pre- and post-treatment CT scans of radiation therapy patients to predict normal lung tissue complications, and the evaluation of reference standards for computer-aided diagnosis (CAD) research. As the local principal investigator for the Lung Image Database Consortium project that spanned 10 years and as the faculty director of the University of Chicago’s Human Imaging Research Office, I have extensive experience with interdisciplinary and multi-institutional image-based projects.
The University of Chicago
Chicago, IL
Ph.D. - Medical Physics
1997
The University of Chicago
Chicago, IL
B.A. - Physics
1987
AI in medical imaging grand challenges: translation from competition to research benefit and patient care.
AI in medical imaging grand challenges: translation from competition to research benefit and patient care. Br J Radiol. 2023 Sep 12; 20221152.
PMID: 37698542
Germline Variants Incidentally Detected via Tumor-Only Genomic Profiling of Patients With Mesothelioma.
Germline Variants Incidentally Detected via Tumor-Only Genomic Profiling of Patients With Mesothelioma. JAMA Netw Open. 2023 08 01; 6(8):e2327351.
PMID: 37556141
Emphysema Detection in the Course of Lung Cancer Screening: Optimizing a Rare Opportunity to Impact Population Health.
Emphysema Detection in the Course of Lung Cancer Screening: Optimizing a Rare Opportunity to Impact Population Health. Ann Am Thorac Soc. 2023 04; 20(4):499-503.
PMID: 36490389
A Competition, Benchmark, Code, and Data for Using Artificial Intelligence to Detect Lesions in Digital Breast Tomosynthesis.
A Competition, Benchmark, Code, and Data for Using Artificial Intelligence to Detect Lesions in Digital Breast Tomosynthesis. JAMA Netw Open. 2023 02 01; 6(2):e230524.
PMID: 36821110
AAPM task group report 273: Recommendations on best practices for AI and machine learning for computer-aided diagnosis in medical imaging.
AAPM task group report 273: Recommendations on best practices for AI and machine learning for computer-aided diagnosis in medical imaging. Med Phys. 2023 Feb; 50(2):e1-e24.
PMID: 36565447
AAPM task group report 273: Recommendations on best practices for AI and machine learning for computer-aided diagnosis in medical imaging.
Hadjiiski L, Cha K, Chan HP, Drukker K, Morra L, N?ppi JJ, Sahiner B, Yoshida H, Chen Q, Deserno TM, Greenspan H, Huisman H, Huo Z, Mazurchuk R, Petrick N, Regge D, Samala R, Summers RM, Suzuki K, Tourassi G, Vergara D, Armato SG. AAPM task group report 273: Recommendations on best practices for AI and machine learning for computer-aided diagnosis in medical imaging. Med Phys. 2022 Dec 24.
PMID: 36565447
Considerations for Imaging of Malignant Pleural Mesothelioma: A Consensus Statement from the International Mesothelioma Interest Group.
Considerations for Imaging of Malignant Pleural Mesothelioma: A Consensus Statement from the International Mesothelioma Interest Group. J Thorac Oncol. 2023 03; 18(3):278-298.
PMID: 36549385
Emphysema Detection in the Course of Lung Cancer Screening: Optimizing a Rare Opportunity to Impact Population Health.
Emphysema Detection in the Course of Lung Cancer Screening: Optimizing a Rare Opportunity to Impact Population Health. Ann Am Thorac Soc. 2022 Dec 09.
PMID: 36490389
Interviewing for residency positions while completing a graduate degree: Considerations for graduate students, mentors, and program directors.
Interviewing for residency positions while completing a graduate degree: Considerations for graduate students, mentors, and program directors. J Appl Clin Med Phys. 2022 08; 23(8):e13700.
PMID: 35699204
The role of imaging in diagnosis and management of malignant peritoneal mesothelioma: a systematic review.
The role of imaging in diagnosis and management of malignant peritoneal mesothelioma: a systematic review. Abdom Radiol (NY). 2022 05; 47(5):1725-1740.
PMID: 35257201
Fellow
Society of Photo-Optical Instrumentation Engineers (SPIE)
2018
Distinguished Investigator
Academy of Radiology Research
2016
Fellow
American Association of Physicists in Medicine
2014
Kurt Rossmann Award for Excellence in Medical Physics Teaching
The University of Chicago
2012
Raine Visiting Professor
University of Western Australia
2009
Kurt Rossmann Award for Excellence in Medical Physics Teaching
The University of Chicago
2002